Unravelling the Zika Virus Genome
The Zika virus (ZIKV) is an arbovirus from the Flaviviridae family and is primarily transmitted via infected mosquitoes. However, ZIKV has also been isolated in semen and so the virus can be transmitted sexually through infected partners. The recent on-going outbreak of ZIKV, which originated in Bahia in Brazil in 2015, has spread rapidly across the Americas and has resulted in more than 1.5 million cases worldwide.
The recent epidemic in the Americas has dominated the headlines due to the high incidence of babies born with microcephaly to ZIKV-infected mothers. Indeed this outbreak has been characterised by an increased prevalence of neurological syndromes such as microcephaly and Guillain-Barre syndrome. In February 2016 the World Health Organisation (WHO) declared the current epidemic to be a global public health emergency, due to the accelerated rate at which ZIKV is spreading, bringing its associated neurological conditions.
Once a relatively obscure virus, the recent devastating outbreaks have thrust ZIKV into the scientific spotlight. Recent research, led...



